New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and ...

New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and ...

Background Recurrent mitral regurgitation (MR) remains a major limitation of mitral valve (MV) repair in patients with ...

Neoadjuvant treatment with a programmed cell death 1 (PD-1) inhibitor induces clinical complete response and leads to organ preservation in a high proportion of patients with early-stage, mismatch ...

TUESDAY, April 29, 2025 (HealthDay News) — A neoadjuvant programmed cell death 1 (PD-1) blockade enables nonoperative management among patients with early-stage mismatch repair-deficient (dMMR) solid ...

NEW YORK – GlaxoSmithKline's checkpoint inhibitor Jemperli (dostarlimab) spared 80 percent of patients with earlier-stage solid tumors characterized by mismatch repair deficiency (dMMR) from needing ...

At birth, people who carry a string of more than 40 CAG repeats within the first exon of the huntingtin gene are all but destined to develop Huntington’s disease. Yet, recent studies are converging on ...

A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...

J. E. Loughery et al., DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response.

Los Angeles Lakers legend Kobe Bryant permanently changed the sneaker industry multiple times over his legendary basketball career. With the help of Nike, the NBA icon's signature line is taking over ...