This paper addresses the optimization of community group-buying distribution paths by considering both cost efficiency and time constraints. Focusing on dense neighbourhoods where such services thrive ...

A clump of proteins seems to be in charge of the level of DNA repair that takes place in our bodies, determining how fast mutations accumulate in our cells over a lifetime – and might thus affect our ...

The final overall survival (OS) results of the FLAURA2 trial support osimertinib plus chemotherapy as the new first-line standard of care for EGFR-mutated non-small cell lung cancer (NSCLC), according ...

Laurence D. Hurst is the author of The Evolution of Imperfection, published by Princeton University Press. This was enabled by funding from The Humboldt Foundation and the European Research Council.

Summary: A massive genomic study has revealed that parental age, ancestry, and smoking habits subtly influence the number of new genetic mutations (de novo mutations) passed from parents to children.

Abstract: The acyclic coloring problem, a specialized area within graph coloring, has numerous applications across diverse fields. It involves assigning colors to the vertices of a graph such that no ...

Understanding how human DNA mutates over time is key to decoding the origins of disease and the path of evolution. But until now, some of the most change-prone regions of our genome have remained out ...

Using sequencing instruments from multiple vendors, scientists from the University of Utah Health, the University of Washington, PacBio, and elsewhere have developed what they claim is the most ...

The William H. Foege Genome Sciences Building at the University of Washington School of Medicine in Seattle contains laboratories, sequencers, computational facilities, and other resources for ...