Syntax Bio, a synthetic biology company programming the next generation of cell therapies, today announced the publication of new research in Science Advances detailing the company’s CRISPR-based ...

The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins.

A new study captures RNA polymerase II in real time, revealing how it accelerates, pauses and shifts speed as it reads DNA.

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

Researchers have identified a stress-activated control mechanism that helps breast cancer cells reshape gene activity to ...

This article examines some of the cell-based approaches that researchers are using to study acquired drug resistance and the ...

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chemotaxis receptors typically mediate biased ...