This year, gene-editing technology was customized to fix mutations in a single patient’s genes for the first time.

Syntax Bio, a synthetic biology company programming the next generation of cell therapies, has published new research in ...

CRISPR powers everything from gene editing to rapid diagnostics, but how did one of its most versatile branches arise? A new Cell study, “Functional RNA splitting drove the evolutionary emergence of ...

CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR RNA-guided cleavage. Type V CRISPR-Cas (Cas12) systems, in particular, ...

DNA is transcribed into RNA, which is then translated into proteins. This is the central dogma of molecular biology – a mantra taught to every biology undergraduate student to be recalled and expanded ...

This paper describes RNA-sensing guide RNAs for controlled activation of CRISPR modification. This works by having an extended guide RNA with a sequence that folds back onto the targeting sequence ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

Department of Botany, Faculty of Science, Dayalbagh Educational Institute, Agra, Uttar Pradesh, India Recent breakthroughs in CRISPR/Cas genome editing have transformed molecular biology research and ...

“The Federal Circuit clarified that for anticipation under § 102, enablement requires only one operable embodiment, not the full scope of claims mandated under § 112.” In a precedential decision ...

At this year’s AACR 2025 (Chicago, IL, USA; 25–30 April), the annual meeting of the American Association for Cancer Research, we picked out our favourite posters from the conference and spoke to their ...

The CRISPR system has transformed many research areas, including cancer and immunology, by providing a simple yet effective genome editing system. Its simplicity has facilitated large-scale ...