The significance of mucin on rectal MRI in patients with locally advanced rectal cancer being considered for watch-and-wait after neoadjuvant therapy. This is an ASCO Meeting Abstract from the 2023 ...
New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and ...
Selecting colorectal cancer (CRC) patients for therapy based on mutational analysis by next generation sequencing: Are we analyzing the appropriate tumor? Background: Colorectal cancer with deficient ...
This project has reached full capacity for the current term. Please check back next semester for updates. Errors in DNA replication occur at the replication fork, leading to misincorporation events, ...
In a paper to be published in the Nov. 25 issue of Proceedings of the National Academy of Sciences, the laboratory of cancer geneticist Alfonso Bellacosa, M.D., of Fox Chase Cancer Center reports new ...
Researchers say they have found a potential explanation for the failures. Checkpoint inhibitor drugs that stimulate the immune system have become a growing success story in the treatment of some ...
Expansions of CTG/CAG trinucleotide repeats, thought to involve slipped DNAs at the repeats, cause numerous diseases including myotonic dystrophy and Huntington's disease. By unknown mechanisms, ...
Brigham researchers' findings from next-generation sequencing suggest that revising current cancer care guidelines could allow approximately 6,000 more patients in the U.S. to benefit from ...
An optimized version of prime editing technology raises the possibility of a one-time treatment for cystic fibrosis. In their 2019 paper, Liu’s team used prime editing to alter the gene mutations ...