New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and ...

New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and ...

In eukaryotes-the group of organisms that include humans –- a key to survival is the ability of certain proteins to quickly and accurately repair genetic errors that occur when DNA is replicated to ...

Background Recurrent mitral regurgitation (MR) remains a major limitation of mitral valve (MV) repair in patients with ...

Mismatch repair protein immunohistochemistry is a widely used method for detecting patients at risk for Lynch syndrome. Recent data suggest that a two-antibody panel approach using PMS2 and MSH6 is an ...

Deficiencies in DNA mismatch repair have been associated with inferior response to 5-FU in colorectal cancer. Pancreatic ductal adenocarcinoma is similarly treated with pyrimidine analogs, yet the ...

Underdiagnosis of Hereditary Breast Cancer: Are Genetic Testing Guidelines a Tool or an Obstacle? Constitutional mismatch repair deficiency (CMMRD) is a highly penetrant cancer predisposition syndrome ...

Please provide your email address to receive an email when new articles are posted on . Mismatch repair (MMR) screening showed MMR deficiency in one-third of sebaceous carcinoma (SC) cases. Rates of ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, No. 8 (Apr. 15, 1993), pp. 3363-3367 (5 pages) Homothallic switching of yeast mating type (MAT) genes is a ...

J. E. Loughery et al., DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response.

Approval Based on Significant Progression Free Survival Findings from Phase 3 KEYNOTE-177 Trial KIRKLAND, QC, March 8, 2021 /CNW/ - Merck (NYSE: MRK), known as MSD outside the United States and Canada ...