When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Human gene maps contain major blind spots because they were built largely from the DNA sequences of people with European ...

The first complete genetic portrait of a so‑called “last Neanderthal” is forcing scientists to redraw the map of our origins, from who we met to how we survived. Instead of a simple story of ...

For decades, the Y chromosome — one of the two human sex chromosomes — has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...

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Sediment DNA also traces life outside the cave. Predators dragged prey into sheltered chambers, humans left waste behind. By ...

The last two decades have seen a revolution in scientists' ability to reconstruct the past. This has been made possible ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.