David Baker's lab at the University of Washington is announcing two major leaps in the field of AI-powered protein design.

Nobel laureate David Baker’s latest foundation model can design proteins that interact to any biomolecule for broad biotech applications.

Phospholipase A2 (PLA2) enzymes are known to play a role in many inflammatory diseases, including asthma, arthritis and atherosclerosis. It then stands to reason that PLA2 inhibitors could represent a ...

Drug molecules and biofuels can be made to order by living cell factories, where biological enzymes do the job. Now researchers at Chalmers University of Technology have developed a computer model ...

A team from the University of Illinois has developed a modeling framework connecting enzyme activity related to photosynthesis to yield. This is the first time a model has tied the dynamic ...

Supercomputers and models aided researchers in understanding enzymes that metabolize cocaine, potentially before molecules of the addictive drug hit the brain. And the use of models has helped ...

Treatment with a novel agent that inhibits the activity of SIRT2, an enzyme that regulates many important cellular functions, reduced neurological damage, slowed the loss of motor function and ...

Coupled oxygen transfer and electron transfer reactions that use cofactors are enzymatic reactions of crucial significance to all lifeforms from bacteria to vertebrates. In the European Journal of ...

Your gut microbes play a major role in how well you absorb nutrients, explaining why identical diets produce very different results.

Pneumonia is a disease that burdens the health care system with more than 1.2 million emergency room visits each year and ...

To better understand PLA2 enzymes and help drive therapeutic drug development, researchers developed 3-D computer models that show exactly how two PLA2 enzymes extract their substrates from cellular ...