Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA. Published online May 16 in the journal Cell, the report describes the ...

Polymerase chain reaction (PCR) is a fundamental molecular biology tool that scientists use to amplify and analyze genetic material, such as DNA and RNA. PCR involves the enzymatic amplification of ...

Correction 6/18/21: The original version of this article stated that polymerase theta was the first mammalian polymerase with the ability to transcribe RNA into DNA. In fact, other polymerases have ...

Scientists have pinpointed precise regions in the human genome where DNA is most likely to develop a mutation.

Bioscientists have uncovered a tiny detail that could help us understand how DNA replicates with such astounding accuracy. When cells reproduce, the internal mechanisms that copy DNA get it right ...

Findings from a preclinical study demonstrate that Omomyc—the only direct MYC inhibitor to have successfully completed a ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 3 (January 18, 2022), pp. 1-7 (7 pages) Elongating RNA polymerase II (Pol II) can be paused or arrested ...