The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...
The RNA helicase DDX3X spends its days unwinding RNA:RNA duplexes and binding key mediators of RNA metabolism. A regulator of RNA transcription, splicing, nuclear export, and translation, DDX3X plays ...
DNA replication origins serve as sites of replicative helicase loading. In all eukaryotes, the six-subunit origin recognition complex (Orc1-6; ORC) recognizes the replication origin. During late ...
Ideaya Biosciences Inc. has announced the selection of a Werner helicase inhibitor development candidate. The candidate is a potent, selective, small-molecule inhibitor of the helicase domain of ...
An international collaborative research team has discovered that G-quadraplex DNA (G4-DNA) accumulates in neurons and dynamically controls the activation and repression of genes underlying long-term ...
March 21, 2012 (San Diego, California) — A novel helicase-primase inhibitor with antiviral activity against the varicella zoster virus might provide an alternative as potent as current treatments for ...
This narrated animation illustrates the process of protein synthesis, starting with chromosomal DNA inside the cell's nucleus. A gene is transcribed into messenger RNA, which leaves the nucleus and ...
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